Magnesium
Correct Answer: Is essential for efficient secretion and peripheral action of PTH
Description: It is uncommon and always due to excessive intake either orally (antacids), rectally (enema) or parenterally. Causes of hypermagnesemia are listed in Box 35.19. Magnesium intoxication causes depression of neuromuscular system, causing lethargy, hypotension, respiratory depression, brady- cardia and weak tendon reflexes. In severe conditions, acute rhabdomyolysis results. Hypermagnesemia induces decrease in serum calcium by inhibiting PTH secretion, which in turn will have deleterious effects.Ref: DM Vasudevan, page no: 412
Category:
Biochemistry
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