**Question:** Chronic lymphoedema of limb is predisposed to all of the following except -

A. Cellulitis
B. Pressure ulcers
C. Deep vein thrombosis (DVT)
D. Malignancy

**Core Concept:**
Chronic lymphoedema is a condition characterized by the accumulation of lymphatic fluid in the tissues due to impaired lymphatic transport. This results in swelling, firmness, and skin changes in the affected limb. Chronic lymphoedema can be caused by various factors, including congenital abnormalities, lymph node surgery, radiation therapy, and infections. The limb is predisposed to various complications due to the compromised immune function and increased vulnerability.

**Why the Correct Answer is Right:**
The correct answer, "D. Malignancy," is the exception in this context because malignant tumors can lead to lymphoedema, not protect the limb from it. Malignant cells can obstruct lymphatic vessels or produce factors that impair lymphatic transport, directly causing lymphoedema.

**Why Each Wrong Option is Incorrect:**
A. Cellulitis: Cellulitis is an infection affecting the skin and underlying tissues, characterized by redness, heat, swelling, pain, and possible fever. Although chronic lymphoedema can make the limb more susceptible to infections, including cellulitis, the statement "Chronic lymphoedema of limb is predisposed to all of the following except cellulitis" is incorrect. In fact, chronic lymphoedema can increase the risk of cellulitis due to impaired immune function and compromised skin barrier.

B. Pressure ulcers: Pressure ulcers, also known as pressure sores or bedsores, result from prolonged pressure on bony prominences. They are unrelated to chronic lymphoedema and are more commonly associated with immobility or poor mobility.

C. Deep vein thrombosis (DVT): DVT is a condition characterized by the formation of blood clots in the deep veins of the limbs, particularly the legs. Although DVT can occur in individuals with chronic lymphoedema, it is not the primary risk associated with chronic lymphoedema. Chronic lymphoedema increases the risk of DVT due to reduced mobility, immobility, or limb swelling, which can cause compression of veins and impair venous return, facilitating the formation of DVT.

**Clinical Pearl:** Chronic lymphoedema is a clinical condition that warrants proper management to prevent and control the complications associated with it. Early recognition, accurate diagnosis, and appropriate treatment can improve the prognosis of patients with chronic lymphoedema.