**Core Concept**
Necrotizing lymphadenitis, also known as Kikuchi disease, is a rare, self-limiting condition characterized by the lymph node inflammation and necrosis. This condition is often associated with viral infections and autoimmune disorders.
**Why the Correct Answer is Right**
Necrotizing lymphadenitis involves the infiltration of lymph nodes by activated T-lymphocytes, which leads to the destruction of lymph node architecture and subsequent necrosis. The exact etiology is still unknown, but it is thought to be triggered by viral infections, such as Epstein-Barr virus, and autoimmune responses. The condition is often associated with fever, sore throat, and cervical lymphadenopathy.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because necrotizing lymphadenitis is not typically associated with bacterial infections, such as tuberculosis or cat-scratch disease.
**Option B:** This option is incorrect because Castleman disease is a distinct lymphoproliferative disorder characterized by the overgrowth of lymphoid tissue, not necrosis.
**Option C:** This option is incorrect because sarcoidosis is a systemic granulomatous disease that affects various organs, including the lymph nodes, but it does not typically cause necrosis.
**Clinical Pearl / High-Yield Fact**
Necrotizing lymphadenitis is often mistaken for tuberculosis or other granulomatous conditions, but the presence of necrosis and the absence of typical granulomas should raise suspicion for this diagnosis.
**Correct Answer: C. Sarcoidosis.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.