A 16-yrs-old girl presents with bowel obstruction. Laparotomy reveals markedly enlarged para-aoic lymph nodes. Biopsy of lymph nodes exhibit a diffuse neoplastic infiltrate of small, round lymphocytes with a “starry sky” appearance on low power. The cytoplasm of some of the lymphocytes is vacuolated and fat stains are positive. You would expect the neoplastic cells to demonstrate a
A 16-yrs-old girl presents with bowel obstruction. Laparotomy reveals markedly enlarged para-aoic lymph nodes. Biopsy of lymph nodes exhibit a diffuse neoplastic infiltrate of small, round lymphocytes with a “starry sky” appearance on low power. The cytoplasm of some of the lymphocytes is vacuolated and fat stains are positive. You would expect the neoplastic cells to demonstrate a
π‘ Explanation
A 16-yrs-old girl presents with bowel obstruction. Laparotomy reveals markedly enlarged para-aoic lymph nodes. Biopsy of lymph nodes exhibit a diffuse neoplastic infiltrate of small, round lymphocytes with a "starry sky" appearance on low power. The cytoplasm of some of the lymphocytes is vacuolated and fat stains are positive. You would expect the neoplastic cells to demonstrate a
β Correct Answer: D. t(8;14) translocation
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