A 16-year-old girl presents with a painfully enlarged lymph node in her right axilla and low grade fever. Peripheral blood counts are within normal limits. The lymph node is biopsied, and numerous granulomas filled with neutrophils and necrotic debris are observed. Which of the following organisms could produce this disease?
A 16-year-old girl presents with a painfully enlarged lymph node in her right axilla and low grade fever. Peripheral blood counts are within normal limits. The lymph node is biopsied, and numerous granulomas filled with neutrophils and necrotic debris are observed. Which of the following organisms could produce this disease?
💡 Explanation
**Core Concept**
Ketosis-prone diabetes, also known as flatbush diabetes, is a rare form of diabetes that is associated with a painful axillary lymphadenitis.
**Why the Correct Answer is Right**
The patient's symptoms, including painfully enlarged lymph node and low-grade fever, in combination with biopsy findings of granulomas filled with neutrophils and necrotic debris, suggest a diagnosis of suppurative lymphadenitis. This condition is often caused by Staphylococcus aureus, a Gram-positive bacterium that can induce a severe inflammatory response and tissue damage.
**Why Each Wrong Option is Incorrect**
* **Option A:** Streptococcus pyogenes is a Gram-positive bacterium that can cause a variety of infections, including pharyngitis and skin infections. However, it is not typically associated with painful lymphadenitis.
* **Option B:** Haemophilus influenzae is a Gram-negative bacterium that can cause infections, particularly in children. However, it is not commonly associated with painful lymphadenitis in this context.
* **Option D:** No organism is listed in option D.
**Clinical Pearl / High-Yield Fact**
When evaluating a patient with painful lymphadenitis, it is essential to consider the possibility of a bacterial infection, particularly Staphylococcus aureus, which can cause significant morbidity if not promptly treated.
**Correct Answer: C. Staphylococcus aureus.**
✓ Correct Answer: A. Baonella henselae
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