Pharmacology Loop diuretics such as furosemide act by : A Decreasing tubular reabsorption of Na+ and increase GFR B Decreasing FP secretion with resultant increase in Na+ and K+excretion C Inhibiting Na+ + K+ – 2Cl– co transporter in the medullary thick ascending limb D Inhibiting Na+ – K+exchange in the collecting duct 💡 Explanation Loop diuretics such as furosemide act by : ✓ Correct Answer: C. Inhibiting Na+ + K+ – 2Cl– co transporter in the medullary thick ascending limb