A 28 year old male complains of glare in both eyes. The cornea shows whorl like opacities of the epithelium. He also gave a history of long term treatment with amiodarone. The most likely diagnosis is –
**Core Concept**
The question is testing the clinical correlation between long-term amiodarone treatment and a specific eye condition characterized by corneal opacities. Amiodarone is an antiarrhythmic medication known to cause various side effects, including ocular toxicity.
**Why the Correct Answer is Right**
Amiodarone-induced corneal microdeposits are a well-documented side effect of long-term amiodarone treatment. These deposits typically appear as whorl-like opacities in the corneal epithelium, which can cause glare and visual disturbances. The exact mechanism of amiodarone-induced corneal toxicity is not fully understood, but it is thought to be related to the accumulation of amiodarone and its metabolites in the cornea.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not directly relate to the known side effects of amiodarone.
**Option B:** This option is incorrect because it is a different condition altogether, and not a known side effect of amiodarone.
**Option C:** This option is incorrect because it is not a known side effect of amiodarone, and the description does not match the clinical presentation.
**Clinical Pearl / High-Yield Fact**
Amiodarone-induced corneal microdeposits are a classic example of a medication-induced ocular toxicity. Long-term treatment with amiodarone should prompt a thorough eye examination to detect any potential corneal changes.
**Correct Answer:** C. Amiodarone-induced corneal microdeposits.