Localised langerhans cells histiocytosis affecting head & neck is –
Correct Answer: Eosinophilic granuloma
Description: Unifocal and multifocal unisystem Langerhans cell histiocytosis(eosinophilic granuloma)is characterised by proliferation of Langerhans cells admixed with variable number of eosinophils , lymphocytes , plasma cell, and neutrophils .Eosinophils are usually , but not always a prominent component of the infiltrate .It typically arises within the medullary cavities of bones, most commonly the calvarium, ribs and femur. ref: Robbins pathologic basis of disease ; 8th edition ; pg 632
Category:
Pathology
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