Loading drug of dose primarily depends on
Correct Answer: Volume of distribution
Description: Loading dose; This is a single or few quickly repeated doses given in the beginning to attain target concentration rapidly.
Loading dose = Target Cp * V /F
Cp - concentration, V - volume of distribution, F - oral bioavailability
Thus, the loading dose is governed only by V and not by Clearance or t1/2
Category:
Pharmacology
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