Given below is the histopathology of liver biopsy of hemochromatosis. Which of the following stain is used?
**Core Concept**
Hemochromatosis is a genetic disorder characterized by excessive iron accumulation in the body, leading to tissue damage. The diagnosis of hemochromatosis involves the detection of iron deposits in tissues.
**Why the Correct Answer is Right**
The correct answer is related to the identification of iron deposits in liver biopsy samples. Prussian blue stain is specifically used for this purpose, as it reacts with iron to produce a blue-colored compound, allowing for the visualization of iron deposits.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it is not specifically related to iron detection.
**Option B:** This option is also incorrect as it does not react with iron to produce a visible compound.
**Option D:** Similarly, this option is incorrect because it is not used for iron detection in liver biopsy samples.
**Clinical Pearl / High-Yield Fact**
Prussian blue stain is a crucial diagnostic tool for detecting iron overload in tissues, particularly in the diagnosis of hemochromatosis.
**Correct Answer:** D. Prussian blue stain.