All are true about amoebic liver abscess except:a) More common in femalesb) More common in left lobe of liverc) Metronidazole is mainstay of treatmentd) Multifocal abscess can not be treated by aspiration

**Core Concept**
Amoebic liver abscess is a complication of amoebiasis caused by the protozoan parasite Entamoeba histolytica. It occurs when the parasite invades the liver through the bloodstream, leading to necrotic lesions and abscess formation.

**Why the Correct Answer is Right**
The correct answer is about the characteristics of amoebic liver abscess. Option C, Metronidazole is mainstay of treatment, is correct because Metronidazole is the first-line treatment for amoebic liver abscess due to its effectiveness against the parasite. Option D, Multifocal abscess can not be treated by aspiration, is also correct as multifocal abscesses are often treated with antiparasitic medication rather than aspiration, which may not be effective in all cases.

**Why Each Wrong Option is Incorrect**
**Option A:** Amoebic liver abscess is more common in males, particularly those with a history of travel to endemic areas or with underlying liver disease. This is due to the parasite's predilection for infecting the liver through the bloodstream.
**Option B:** Amoebic liver abscess is more common in the right lobe of the liver, not the left lobe. The right lobe is more frequently affected due to its larger size and increased blood flow.

**Clinical Pearl / High-Yield Fact**
Amoebic liver abscess often presents with right upper quadrant pain, fever, and hepatomegaly. It is essential to consider the diagnosis in patients with a history of travel to endemic areas or with underlying liver disease.

**Correct Answer:** C. Metronidazole is mainstay of treatment