Lipoprotein with seavenging action is:
Correct Answer: HDL
Description: A i.e. HDLHDL scavanges body cholesterol and blood vessel wall cholesterol by 'reverse cholesterol transpo'-[Shinde P- 3861 The transpo of cholesterol from the tissue to liver is known as 'reverse cholesterol transpo'.* Class B scavenger receptor Bl (SR -B1) and ATP binding cassette transpoer Al (ABCA 1) are involved in reverse cholesterol transpoQ.* Reverse cholesterol transpo involves efflux of cholesterol from peripheral cells to HDL, esterification of cholesterol by PCAT (phosphatidyl choline: cholesterol acyl transferase), binding of cholesterol ester rich HDL (HDL-2) to liver and steroidogenic cells, the selective transfer of the cholesteryl esters into these cells and the release of lipid depleted HDL (HDL-3).The efflux of cholesterol from peripheral cells is mediated by ABCA-1 and the uptake of cholesteryl ester by liver is mediated by SRBI. Hepatic lipase degrade both triacyl glycerol and phospholipid, & paicipate in conversion of HDL2 to HDL3, (HDL cycle). HDL2 concentrations are inversely related to incidence of coronary atherosclerosis. HDLc (HDLG) is found in diet induced hyper cholesterolemic animals. It is rich in cholesterol & has only apo E apoprotein.
Category:
Biochemistry
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