Leucovorin is used to decrease the toxicity of
Correct Answer: Methotrexate
Description: Ref: Katzung 10th/887; KDT 6/e 823 Toxicity of methotrexate can be reversed by the administration of 5-formyltetrahydrofolate (leucovorin or citrovorum factor). Folic acid in the diet is in dihydrofolate form. It is ineffective in reversing methotrexate toxicity.
Category:
Pharmacology
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