**Core Concept**
Left-sided portal hypertension is a condition where there is increased pressure in the portal vein and its tributaries on the left side of the body. This is often due to an obstruction in the portal venous system, such as a thrombosis or a tumor, which can lead to the formation of varices and ascites.

**Why the Correct Answer is Right**
The correct treatment for left-sided portal hypertension involves addressing the underlying cause of the obstruction. Since the obstruction is located on the left side, a shunt procedure that connects the left portal vein to the inferior vena cava (IVC) would be most effective in reducing the pressure in the portal vein. This is because the IVC is a large vein that can accommodate increased blood flow from the left portal vein, thereby reducing the pressure and preventing further complications.

**Why Each Wrong Option is Incorrect**
**Option A:** Surgical ligation of the left portal vein would actually worsen the condition by completely blocking blood flow, leading to further increase in pressure and potentially causing liver failure.
**Option B:** Transjugular intrahepatic portosystemic shunt (TIPS) is a procedure that connects the hepatic vein to the portal vein, but it would not be effective in left-sided portal hypertension since the obstruction is located on the left side.
**Option C:** Endoscopic variceal ligation is a treatment for varices, but it does not address the underlying cause of left-sided portal hypertension.

**Clinical Pearl / High-Yield Fact**
When treating portal hypertension, it is essential to identify the underlying cause of the obstruction and address it promptly to prevent further complications.

**Correct Answer:** C.