**Core Concept**
HIV transmission rates vary depending on several factors, including the mode of transmission, viral load, and individual susceptibility. Understanding the relative risks of different transmission routes is crucial for prevention and public health strategies.

**Why the Correct Answer is Right**
The least rates of HIV transmission are seen through breastfeeding from an HIV-positive mother. This is because the virus is present in breast milk, but the risk of transmission can be significantly reduced with antiretroviral therapy (ART) and other preventive measures. The risk of HIV transmission through breastfeeding is estimated to be around 5-10% without ART, making it a lower risk compared to other modes of transmission, such as mother-to-child during pregnancy (around 15-30%), during delivery (around 20-30%), or through sexual contact (around 10-20% per year).

**Why Each Wrong Option is Incorrect**
**Option A:** This option is not provided.
**Option B:** This option is not provided.
**Option C:** This option is not provided.
**Option D:** This option is not provided.

**Clinical Pearl / High-Yield Fact**
It's essential to note that the risk of HIV transmission through breastfeeding can be minimized with ART and other preventive measures, such as Exclusive Formula Feeding (EFF) for at least 6 months. This highlights the importance of comprehensive HIV prevention strategies for mothers and their infants.

**Correct Answer: D. Breastfeeding is not provided as an option, so it seems there is an error in the question provided.