LDH isoenzyme specific for heart is –
Correct Answer: LDH1
Description: Ans. is 'a' i.e., LDH1* Lactate Dehydrogenase converts pyruvate to lactate.* It is present in cytoplasm of cells* It is a tetramer. Two subunits H and M in various combinations make up the various isoenzymes of LDHLDH ISOENZYMESUBUNITSLOCATIONLDH 1H4Heart, RBC, BrainLDH 2H3M1Reticuloendothelial cellsLDH3H2M2LungsLDH4H1M3Kidneys, placenta, PancreasLDH 5M4Liver and skeletal muscle* In blood generally LDH 2 isoenzyme concentration is higher. In myocardial infarction, LDH1 concentration is increased. This LDH 1 being more than LDH2 is called as flipped pattern of LDH which is suggestive of myocardial infarction.
Category:
Biochemistry
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