## Core Concept
The core concept being tested here is the historical eradication of smallpox, a highly infectious and often fatal disease caused by the variola virus. Smallpox was declared eradicated by the World Health Organization (WHO) in 1980 following a global vaccination campaign. The question pertains to the last naturally occurring case of smallpox.

## Why the Correct Answer is Right
The correct answer, , is right because the last naturally occurring case of smallpox was reported from Somalia in 1977. A 23-year-old male named Ali Maow Maalin from the town of Alirab, near Merca, Somalia, was diagnosed with smallpox on October 26, 1977. This case marked the end of naturally occurring smallpox infections worldwide.

## Why Each Wrong Option is Incorrect
- **Option A:** This option is incorrect because it does not correspond to any well-documented location related to the last case of smallpox.
- **Option B:** This option is incorrect for the same reason as Option A; it does not match the known historical data on the eradication of smallpox.
- **Option D:** This option is incorrect as it also does not align with the historical facts surrounding the last naturally occurring case of smallpox.

## Clinical Pearl / High-Yield Fact
A key point to remember is that smallpox was officially declared eradicated in 1980, and the last natural case was in Somalia in 1977. This achievement was a significant milestone in public health, demonstrating the power of coordinated global vaccination efforts.

**Correct Answer: C. Somalia**