Lactic acidosis in thiamine deficiency is due to which enzyme dysfunction?
Correct Answer: Pyruvate Dehydrogenase
Description: In Thiamine deficiency, PDH reaction is defective. So, pyruvate is converted to lactic acid.
Causes of inhibition of PDH leading to lactic acidosis:
Inherited PDH deficiency
Thiamine deficiency
Alcoholics due to thiamine deficiency
Arsenite and Mercury poisoning
Harper 30th edition
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now