Medical MCQ-L-Dopa is combined with carbidopa in the treatment of parkinsonism to -

L-Dopa is combined with carbidopa in the treatment of parkinsonism to –

Decrease the efficacy of levodopa

Increase the dose of levodopa required

Inhibit conversion of levodopa to dopamine in the CNS

Question Category:

Pharmacology

Correct Answer:

Decrease the efficacy of levodopa

Description:

Ans. is 'b' i.e., Inhibit peripheral decarboxylation of levodopa Carbidopa is combined with levodopa to inhibit peripheral decarboxylation of levodopa and make more levodopa available to cross the blood brain barrier to reach its site of action.

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