## **Core Concept**
Krukenberg spindles refer to a specific type of deposit or accumulation found in the eye, particularly associated with pigment dispersion syndrome. These spindles are characteristic pathological findings.

## **Why the Correct Answer is Right**
Krukenberg spindles are formed by the accumulation of pigment on the posterior surface of the cornea. This condition is often associated with pigment dispersion syndrome, where pigment from the iris flakes off and deposits on various structures within the eye, including the cornea. The spindles are typically seen on the endothelial surface of the cornea and are a result of pigmentary dispersion.

## **Why Each Wrong Option is Incorrect**
- **Option A:** Incorrect because while pigment dispersion does affect the eye, Krukenberg spindles specifically refer to corneal involvement, not general iris damage or pigment loss.
- **Option B:** Incorrect as it does not accurately describe the specific association of Krukenberg spindles with corneal pigment deposition.
- **Option D:** Incorrect because it does not correctly identify the specific ocular structure associated with Krukenberg spindles.

## **Clinical Pearl / High-Yield Fact**
A key clinical correlation to remember is that Krukenberg spindles are a diagnostic feature of pigment dispersion syndrome, which can lead to secondary glaucoma. Therefore, identifying these spindles during an ocular examination can be crucial for diagnosing and managing the condition.

## **Correct Answer:** C. Krukenberg spindles are pigment deposits on the cornea.