**Question:** Keratoconus is seen in: March 2010

**Core Concept:** Keratoconus is a progressive degenerative disorder of the cornea characterized by thinning and bulging of the cornea, leading to a cone-shaped cornea. It results in astigmatism, vision distortion, and irregular astigmatism.

**Why the Correct Answer is Right:** Keratoconus is primarily seen in young adults, often affecting both eyes. The progression of the disease peaks in the third to fifth decade of life, hence the term "March 2010" refers to the peak age group affected by keratoconus. The condition predominantly affects people with a genetic predisposition, particularly those with a family history of keratoconus, making Option D (genetic) the correct answer.

**Why Each Wrong Option is Incorrect:**

A. **Age-related:** Keratoconus primarily affects young adults and not the elderly, making Option A incorrect.
B. **Secondary:** Keratoconus is a primary disorder, not a secondary complication of another disease, making Option B incorrect.
C. **Male-only:** Keratoconus affects both males and females equally, making Option C incorrect.

**Clinical Pearl:**
Keratoconus is a chronic progressive disease that requires regular monitoring and management. Corneal transplantation is a common treatment option for advanced cases.

**Correct Answer:** D. Genetic