Keratic precipitates are on which layer of the cornea –
**Core Concept**
Keratic precipitates (KPs) are proteinaceous and cellular deposits on the cornea, often seen in uveitis. The **cornea** is composed of several layers, including the epithelium, Bowman's layer, stroma, Descemet's membrane, and endothelium.
**Why the Correct Answer is Right**
Keratic precipitates are typically found on the **endothelial layer** of the cornea, which is the innermost layer. This layer is in close proximity to the **aqueous humor**, allowing for the deposition of inflammatory cells and proteins. The endothelial layer plays a crucial role in maintaining corneal transparency.
**Why Each Wrong Option is Incorrect**
**Option A:** The epithelium is the outermost layer, and while it can be involved in various corneal pathologies, it is not the typical location for keratic precipitates.
**Option B:** Bowman's layer is an acellular layer, making it an unlikely site for cellular deposits.
**Option C:** The stroma can be involved in corneal pathologies, but it is not the primary location for keratic precipitates.
**Clinical Pearl / High-Yield Fact**
Keratic precipitates are a key diagnostic feature of uveitis, and their location on the endothelial layer can help differentiate between different types of uveitis.
**Correct Answer:** D. Endothelium