Medical MCQ-Kamlesh, a 2 year old girl, has Down's syndrome. Her karyotype is 21/21 translocation. What is the risk ofrecurrence in subsequent pregnancies if the father is a balanced translocation carrier :

Kamlesh, a 2 year old girl, has Down’s syndrome. Her karyotype is 21/21 translocation. What is the risk ofrecurrence in subsequent pregnancies if the father is a balanced translocation carrier :

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Question Category:

Gynaecology & Obstetrics

Correct Answer:

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Description:

Down Syndrome– (Trisomy 21)Seen in 11n 800 to 1000 newborns M/C Nonlethal trisomy Risk of Down syndrome increases with increase in maternal age At maternal age of 35 years, the risk of having a baby with Down syndrome is 1:365. to 1:400.Recurrent Risk of Down’s syndrome

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