**Core Concept**
Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by inflammation and destruction of joints, leading to pain, stiffness, and deformity. The disease primarily affects the small joints of the hands and feet.

**Why the Correct Answer is Right**
Rheumatoid arthritis is known to predominantly involve the small joints of the hands and feet, such as the proximal interphalangeal (PIP) and metacarpophalangeal (MCP) joints of the hands, and the interphalangeal (IP) and metatarsophalangeal (MTP) joints of the feet. This is due to the presence of rheumatoid factor, an antibody that targets the Fc region of IgG and contributes to joint inflammation.

**Why Each Wrong Option is Incorrect**
**Option A:**
This option is incorrect as it is a common joint involved in rheumatoid arthritis.

**Option B:**
This option is incorrect as it is a common joint involved in rheumatoid arthritis.

**Option C:**
This option is incorrect as it is a common joint involved in rheumatoid arthritis.

**Clinical Pearl / High-Yield Fact**
It is essential to note that while the small joints of the hands and feet are primarily affected, rheumatoid arthritis can also involve other joints, such as the knees, elbows, wrists, and ankles, in some cases.

**Correct Answer: D.**