**Core Concept**
Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by inflammation and destruction of synovial joints, leading to pain, stiffness, and deformity. The disease primarily affects the small joints of the hands and feet, but can also involve other joints.

**Why the Correct Answer is Right**
Rheumatoid arthritis is known to affect the joints of the hands, feet, wrists, knees, elbows, ankles, and shoulders. The disease causes inflammation of the synovium, leading to cartilage and bone destruction. The involvement of these joints is due to the presence of rheumatoid factor and anti-CCP antibodies, which are specific to RA. The disease process involves the activation of T-cells and macrophages, which produce pro-inflammatory cytokines, leading to joint damage.

**Why Each Wrong Option is Incorrect**
**Option A:** This joint is not typically involved in rheumatoid arthritis.
**Option B:** This joint is a common site for rheumatoid arthritis involvement.
**Option C:** This joint is a typical site for rheumatoid arthritis involvement.

**Clinical Pearl / High-Yield Fact**
It's essential to remember that rheumatoid arthritis can also affect non-joint structures, such as the eyes, lungs, and skin, which are often referred to as extra-articular manifestations.

**Correct Answer:** A.