“Johnes” Bacillus is:
**Core Concept**
Johnes' Bacillus is a type of bacteria that causes Johne's disease, a chronic gastrointestinal disease primarily affecting ruminant animals such as cattle, goats, and sheep. The disease is characterized by the formation of granulomas in the small intestine, leading to malabsorption and weight loss.
**Why the Correct Answer is Right**
The correct answer is related to the pathophysiology of Johne's disease. Johne's disease is caused by *Mycobacterium avium subsp. paratuberculosis*, a member of the Mycobacterium avium complex (MAC). The bacteria infect the intestinal epithelial cells, leading to the formation of granulomas and subsequent malabsorption. The disease is often diagnosed through the isolation of the bacteria from fecal samples or through the detection of antibodies against the bacteria in the animal's serum.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specify the correct genus and species of the bacteria causing Johne's disease. *Mycobacterium avium* is a different species that can cause a different type of disease in humans and animals.
**Option B:** This option is incorrect because it is not a recognized species of Mycobacterium that causes Johne's disease. *Mycobacterium bovis* is a different species that can cause tuberculosis in animals and humans.
**Option C:** This option is incorrect because it is not a valid scientific name for the bacteria causing Johne's disease. *Mycobacterium avium subsp. paratuberculosis* is the correct name.
**Clinical Pearl / High-Yield Fact**
Johne's disease is often referred to as "shipman's disease" due to its historical association with the cattle industry. The disease is typically diagnosed through fecal culture or serological tests, and it can be prevented through good hygiene practices and vaccination.
**Correct Answer: D. Mycobacterium avium subsp. paratuberculosis.**