Johne’s bacillus is –
## **Core Concept**
Johne's bacillus, also known as *Mycobacterium avium* subspecies *paratuberculosis* (*MAP*), is a type of bacterium that causes **Johne's disease**, a chronic and often fatal condition primarily affecting the intestines of ruminant animals like cattle, sheep, and goats.
## **Why the Correct Answer is Right**
The correct answer, *Mycobacterium avium* subspecies *paratuberculosis* (*MAP*), is the causative agent of Johne's disease. This bacterium is a member of the *Mycobacterium* genus, which includes other notable pathogens like *Mycobacterium tuberculosis*. *MAP* primarily infects the ileum and sometimes the jejunum, leading to chronic inflammation and thickening of the intestinal wall, which results in malabsorption and weight loss.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because it does not specify *Mycobacterium avium* subspecies *paratuberculosis*, which is the known causative agent of Johne's disease.
- **Option B:** This option is incorrect as it does not correspond to the scientifically accepted nomenclature for Johne's bacillus.
- **Option D:** This option is incorrect because it does not accurately represent *Mycobacterium avium* subspecies *paratuberculosis*.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that Johne's disease is a significant concern in veterinary medicine due to its impact on livestock productivity and the difficulty in controlling its spread. The disease presents with symptoms such as chronic diarrhea, weight loss, and sometimes death. Interestingly, there has been some debate and research into a potential link between *MAP* and **Crohn's disease** in humans, although this remains a topic of investigation and controversy.
## **Correct Answer:** B. Mycobacterium avium paratuberculosis.