Jaundice in the new–born is physiological when –
**Core Concept**
Jaundice in newborns is a common condition that can be physiological or pathological, depending on the underlying cause. **Physiological jaundice** occurs due to the breakdown of red blood cells and the liver's immaturity to process **bilirubin**.
**Why the Correct Answer is Right**
The correct answer choice is related to the timing and characteristics of physiological jaundice, which typically appears after 24 hours of life, peaks at 3-5 days, and resolves by 7-10 days. This pattern is due to the balance between **bilirubin production** and the liver's increasing ability to conjugate bilirubin, making it water-soluble for excretion.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because jaundice appearing in the first 24 hours of life is more likely to be pathological.
**Option B:** Incorrect as it doesn't specify the correct timeframe for physiological jaundice.
**Option D:** Incorrect because it doesn't accurately describe the typical duration of physiological jaundice.
**Clinical Pearl / High-Yield Fact**
Physiological jaundice is a common condition in newborns, and it's essential to distinguish it from pathological causes, which may require immediate medical attention.
**Correct Answer:** D. appears after 24 hours, peaks by 3-5 days and resolves by 7-10 days.