Jamaican vomiting sickness cause by unripe apple fruit toxin?
**Core Concept**
The question is testing knowledge of toxicology, specifically the toxin responsible for Jamaican vomiting sickness. This condition is caused by consuming unripe or green fruit of a particular tree. The underlying principle involves understanding the toxic compounds found in certain plants.
**Why the Correct Answer is Right**
Jamaican vomiting sickness is caused by hypoglycin, a toxin found in the unripe fruit of the **ackee tree** (Jamaican fruit). Hypoglycin inhibits the enzyme **acetyl-CoA dehydrogenase**, leading to severe vomiting and hypoglycemia. This toxin is particularly dangerous because it can cause severe metabolic disturbances.
**Why Each Wrong Option is Incorrect**
**Option A:** This choice is incorrect because it does not specify the correct toxin or fruit.
**Option B:** Incorrect as it is not related to the ackee fruit or its toxin.
**Option C:** This is also incorrect as it is not the cause of Jamaican vomiting sickness.
**Option D:** Incorrect, as the toxin is not from an apple fruit.
**Clinical Pearl / High-Yield Fact**
Remember, Jamaican vomiting sickness is a significant public health concern in areas where the ackee fruit is commonly consumed. The key to prevention is avoiding the consumption of unripe or green ackee fruit.
**Correct Answer:** D. Hypoglycin from unripe ackee fruit, not apple.