Vaccination causing intussusception is
**Core Concept**
Intussusception is a serious medical condition where a part of the intestine invaginates into another segment, leading to bowel obstruction and potentially life-threatening complications. Vaccination-related intussusception is a rare but serious adverse event associated with certain vaccines.
**Why the Correct Answer is Right**
Rotavirus vaccine, introduced in the early 2000s, has been linked to an increased risk of intussusception in infants. The exact mechanism is not fully understood, but it is believed to be related to the presence of viral particles or components that may stimulate an immune response leading to intussusception. The risk is highest within 6-14 days after the first dose of the vaccine, particularly with the oral rotavirus vaccine.
**Why Each Wrong Option is Incorrect**
**Option A:** Parvovirus is not associated with intussusception. It's known for causing Fifth disease and can lead to complications in individuals with certain underlying medical conditions.
**Option B:** Parvovirus is not linked to intussusception; it's a different virus altogether.
**Option C:** Poliovirus vaccine does not cause intussusception. Oral poliovirus vaccine (OPV) has been associated with vaccine-associated poliomyelitis, but not intussusception.
**Option D:** BCG (Bacillus Calmette-GuΓ©rin) vaccine, used against tuberculosis, does not cause intussusception. It's associated with other adverse effects like BCGitis or erythema.
**Clinical Pearl / High-Yield Fact**
Be aware of the rare but serious risk of intussusception associated with the rotavirus vaccine, particularly in the first few weeks after vaccination. Monitor for symptoms like abdominal pain, vomiting, and bloody stools in infants who have received the rotavirus vaccine.
**β Correct Answer: A. Rotavirus**