Intrinsic factor in stomach is secreted by
**Core Concept**
The **intrinsic factor** is a glycoprotein produced in the stomach, essential for the absorption of **vitamin B12**. It binds to vitamin B12 in food and facilitates its absorption in the **ileum**. This process is crucial for the prevention of **pernicious anemia**.
**Why the Correct Answer is Right**
The correct answer is related to the cells responsible for secreting intrinsic factor. **Parietal cells** in the stomach lining secrete intrinsic factor, which then binds to vitamin B12, allowing it to be absorbed in the intestine. This is a critical step in the metabolism of vitamin B12.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specify the correct cell type responsible for intrinsic factor secretion.
**Option B:** This option is also incorrect as it is not related to the secretion of intrinsic factor.
**Option D:** Similarly, this option is incorrect as it does not accurately describe the source of intrinsic factor.
**Clinical Pearl / High-Yield Fact**
Intrinsic factor deficiency leads to **pernicious anemia**, characterized by megaloblastic anemia due to vitamin B12 deficiency. This condition can be treated with vitamin B12 supplements.
**Correct Answer:** C. Parietal cells.