The foetus born during the 6th month of intrauterine life will NOT be able to survive due to –
## **Core Concept**
The question tests the understanding of fetal development and viability, specifically focusing on the critical period when a fetus can survive outside the womb. This period is crucial for understanding neonatal care and the implications of preterm birth.
## **Why the Correct Answer is Right**
The correct answer, **C. Pulmonary surfactant deficiency**, is right because pulmonary surfactant production is critical for reducing surface tension within the lungs, thereby preventing lung collapse during expiration. This production begins around the 24th to 28th week of gestation. Before this period, especially around the 6th month (which corresponds to approximately 24 weeks of gestation), the fetus's lungs are not mature enough to produce sufficient surfactant, making it difficult for the newborn to breathe and maintain lung inflation.
## **Why Each Wrong Option is Incorrect**
- **Option A: Immature kidneys** - While it's true that kidney development and function are crucial, the primary issue with survival outside the womb at 6 months gestation is not directly related to kidney function, as the fetus can survive with relatively immature kidneys for some period with proper care.
- **Option B: Inadequate glycogen stores** - Although glycogen stores are important for newborn energy, the immediate cause of non-survival at 6 months gestation is more directly related to respiratory issues than metabolic ones.
- **D. Inability to regulate body temperature** - This is a challenge for preterm infants but is not the primary reason a fetus born at 6 months gestation cannot survive; it is one of several contributing factors.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that the age of viability, when a fetus can potentially survive outside the womb with medical assistance, generally starts around 28 weeks of gestation. This is closely related to **pulmonary surfactant** production. Before 28 weeks, the risk of severe respiratory distress syndrome (RDS) due to surfactant deficiency is very high.
## **Correct Answer: C. Pulmonary surfactant deficiency**