Intratubular germ cell tumor found adjacent to :
Correct Answer: Dysgerminoma
Description: Ans is b ie. dysgerminoma lntratubular germ cell neoplasia (ITGCN) is regarded as the preinvasive stage of testicular germ cell tumors (also k/a carcinoma in situ of testis ) It is the precursor of all germ cell tumors except? - pediatric yolk sac tumors and teratomas and - adult spermatocytic seminomas. ITGCN can be found in testicular tissue adjacent to GCTs in approximately 90 percent of adult cases. ITCGN is encountered with a high frequency in the following conditions, listed in order of increasing risk: cryptorchidism, prior germ cell tumors, strong family history of germ cell tumor, androgen insensitivity syndrome, and gonadal dysgenesis syndrome. Untreated ITGCN progresses to invasive germ cell tumor in approximately 50% of cases over 5 years of follow-up and it has also been proposed that practically all patients with ITGCN eventually develop invasive tumors. If ITGCN is identified, it is treated by low-dose radiotherapy, which destroys the germ cells yet maintains the androgen production of the Leydig cells.
Category:
Surgery
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now