Which of the following is given in the form of an intralesional injection to treat keloid?
**Core Concept**
Intralesional injections are a treatment modality used to deliver medications directly into a specific lesion, allowing for high concentrations of the drug to be delivered with minimal systemic side effects. In the context of keloid treatment, intralesional injections are used to reduce the size and recurrence of keloid scars.
**Why the Correct Answer is Right**
Steroid intralesional injections are a common treatment for keloid scars. They work by reducing inflammation and modulating the immune response, thereby decreasing the scarring process. The injection of steroids directly into the keloid lesion allows for a high concentration of the medication to be delivered, minimizing systemic side effects. This targeted approach can lead to significant reduction in keloid size and recurrence rates.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as intralesional 5-fluorouracil is primarily used to treat actinic keratosis and superficial basal cell carcinoma, not keloids.
**Option B:** This option is incorrect as intralesional verapamil is used to treat hypertrophic scars, but it's not the first-line treatment for keloids, and it's less effective compared to steroids.
**Option C:** This option is incorrect as intralesional interferon is used to treat warts, not keloids.
**Clinical Pearl / High-Yield Fact**
Steroid intralesional injections are a first-line treatment for keloid scars, and they should be considered for patients with large or recurrent keloids, especially those who have failed other treatments. The injections should be performed by a dermatologist or a surgeon with expertise in scar management.
**Correct Answer:** C. Steroid intralesional injection.