Insulin promotes lipogenesis by all except

Correct Answer: Inhibiting pyruvate dehydrogenase
Description: BE CAREFUL: Questions says EXCEPT Insulin: Decreases cAMP Increases glucose uptake into peripheral tissues by recruiting GLUT-4 Increase the formation of Acetyl CoA by increasing the action of enzyme - Pyruvate Dehydrogenase i.e. Link reaction So, option C is wrong as insulin activates enzyme of Link reaction i.e. Pyruvate Dehydrogenase (not inhibits). Extra information: Insulin activates: All Anabolic pathways (HMP, Glycogenesis, Fatty Acid Synthesis, Cholesterol Synthesis and TG Synthesis). Two Catabolic pathway enzymes i.e. Glycolysis and Link reaction.
Category: Biochemistry
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