All the following drugs are mono amino oxidase inhibitors except
**Question:** All the following drugs are monoamine oxidase inhibitors except
A. Tranylcypromine
B. Isocarboxazid
C. Phenelzine
D. Fluoxetine
**Core Concept:**
Monoamine oxidase inhibitors (MAOIs) are a class of antidepressants that work by inhibiting the enzyme monoamine oxidase (MAO). This results in an increase in the levels of neurotransmitters such as serotonin, norepinephrine, and dopamine, which leads to improved mood and reduced symptoms of depression and anxiety.
**Why the Correct Answer is Right:**
Drug D (Fluoxetine) is not an MAOI. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI), which is a different class of antidepressants that work by inhibiting the reuptake of serotonin into the presynaptic neuron, thereby increasing its availability in the synaptic cleft.
**Why Each Wrong Option is Incorrect:**
A. Tranylcypromine (option A) is an MAOI due to its inhibitory action on MAO enzyme, making it a correct answer.
B. Isocarboxazid (option B) is an MAOI due to its inhibitory action on MAO enzyme, making it a correct answer.
C. Phenelzine (option C) is an MAOI due to its inhibitory action on MAO enzyme, making it a correct answer.
**Why the Correct Answer is Right:**
Fluoxetine (option D), on the other hand, does not inhibit the MAO enzyme. It is an SSRI, as mentioned earlier.
**Core Concept (in Markdown format):**
Monoamine oxidase inhibitors (MAOIs) are drugs that inhibit the enzyme monoamine oxidase (MAO), which results in increased levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain.
**Why the Correct Answer is Right:**
Fluoxetine (option D) is a selective serotonin reuptake inhibitor (SSRI). As mentioned earlier, SSRIs work by inhibiting the reuptake of serotonin into the presynaptic neuron, whereas MAOIs work by inhibiting MAO enzyme.
**Why Each Wrong Option is Incorrect:**
Tranylcypromine (option A), isocarboxazid (option B), and phenelzine (option C) are all MAOIs due to their inhibitory action on the MAO enzyme. They belong to the same class as Fluoxetine (option D) which is an SSRI.
**Why the Correct Answer is Right:**
Fluoxetine (option D) is a selective serotonin reuptake inhibitor (SSRI) which works by inhibiting the reuptake of serotonin into the presynaptic neuron, while MAOIs like Tranylcypromine (option A), Isocarboxazid (option B), and Phenelzine (option C) work by inhibiting the