Study the following carefully -Read the pedigree. Inheritance pattern of the disease in the family is –
**Core Concept**
The pedigree provided represents a family with a genetic disorder, where the mode of inheritance needs to be determined. The pedigree shows multiple generations with affected individuals, and the pattern of inheritance needs to be analyzed to identify the underlying genetic pattern.
**Why the Correct Answer is Right**
The pedigree shows an autosomal dominant pattern of inheritance, where a single copy of the mutated gene is sufficient to cause the disease. The affected individuals in the pedigree have at least one affected parent, and the disease is present in every generation. This is characteristic of an autosomal dominant pattern, where the affected individual has a 50% chance of passing the mutated gene to each offspring.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the pedigree does not show a clear pattern of autosomal recessive inheritance, where two copies of the mutated gene are required to cause the disease.
**Option B:** This option is incorrect because the pedigree does not show a clear pattern of X-linked inheritance, where the disease is caused by a mutation on the X chromosome.
**Option C:** This option is incorrect because the pedigree does not show a clear pattern of mitochondrial inheritance, where the disease is caused by a mutation in the mitochondrial DNA.
**Clinical Pearl / High-Yield Fact**
A classic feature of autosomal dominant inheritance is the presence of affected individuals in every generation, with each affected individual having a 50% chance of passing the mutated gene to each offspring.
**Correct Answer: B. Autosomal Dominant**