Inflammatory cell that will be seen after 2 days of acute appendicitis is
**Core Concept**
Inflammation of the appendix, known as acute appendicitis, involves an initial phase of tissue damage and an immune response. The body's response to this injury includes the recruitment of various inflammatory cells.
**Why the Correct Answer is Right**
The correct answer is polymorphonuclear leukocytes (PMNs), also known as neutrophils. These cells are the primary inflammatory cells seen in the initial phase of acute appendicitis, typically within 24-48 hours after the onset of symptoms. Neutrophils are attracted to the site of injury by chemokines and cytokines, such as IL-8 and TNF-alpha, which are released by damaged tissue and resident immune cells. The influx of neutrophils helps to eliminate bacteria and debris from the site of injury.
**Why Each Wrong Option is Incorrect**
**Option A:** Lymphocytes are typically seen in the later stages of inflammation, around 3-5 days after the onset of appendicitis. They play a key role in the adaptive immune response and are involved in the resolution of inflammation.
**Option B:** Eosinophils are not typically associated with acute appendicitis and are more commonly seen in allergic reactions and parasitic infections.
**Option C:** Macrophages are also not the primary inflammatory cells seen in the initial phase of acute appendicitis, but rather play a role in the later stages of inflammation, helping to clean up debris and facilitate the adaptive immune response.
**Clinical Pearl / High-Yield Fact**
In acute appendicitis, the presence of polymorphonuclear leukocytes in the peritoneal fluid or tissue is a key diagnostic feature, often seen on histopathological examination of the appendix or peritoneal fluid.
**Correct Answer:** D.