## **Core Concept**
Chronic inflammation is a prolonged inflammatory response characterized by the presence of **mononuclear cells** (like macrophages, lymphocytes) and **fibrosis**. It involves tissue damage and repair processes. Key features include angiogenesis, granulation tissue formation, and eventual scarring.

## **Why the Correct Answer is Right**
The correct answer, ., represents an option that does not typically occur in chronic inflammation. In chronic inflammation, there is usually a shift from **acute inflammatory cells** like neutrophils to mononuclear cells.

## **Why Each Wrong Option is Incorrect**
- **Option A:** Typically represents a feature seen in chronic inflammation, such as the presence of macrophages and lymphocytes.
- **Option B:** Often associated with chronic inflammation due to the involvement of granulation tissue and fibrosis.
- **Option C:** Can be a part of chronic inflammation, reflecting ongoing tissue injury and repair.

## **Clinical Pearl / High-Yield Fact**
A key point to remember is that **chronic inflammation** often leads to **fibrosis**, which can cause organ dysfunction if severe. For example, liver cirrhosis results from chronic liver inflammation.

## **Correct Answer: .**