**Core Concept**
MRSA (Methicillin-resistant Staphylococcus aureus) is a type of bacteria that has developed resistance to several antibiotics, making it difficult to treat. In healthcare settings, MRSA can spread from person to person through direct or indirect contact with contaminated surfaces or medical equipment.

**Why the Correct Answer is Right**
The best way to control MRSA infection is through rigorous infection control practices, including hand hygiene, use of personal protective equipment (PPE), and environmental cleaning and disinfection. This is because MRSA can survive on surfaces for extended periods and can be spread through touch or contact with contaminated surfaces. The Centers for Disease Control and Prevention (CDC) recommend using a combination of cleaning and disinfection methods, including using a quaternary ammonium compound (quat) or a hydrogen peroxide-based disinfectant, to effectively kill MRSA.

**Why Each Wrong Option is Incorrect**
**Option A:** Using antibiotics alone is not effective in controlling MRSA infection, as the bacteria have developed resistance to multiple antibiotics.
**Option B:** Isolating the patient alone is not sufficient to control the outbreak, as MRSA can be spread through contaminated surfaces and equipment.
**Option C:** Using antiseptic wipes on surfaces may not be effective in controlling MRSA, as the bacteria can form biofilms that are resistant to antiseptics.

**Clinical Pearl / High-Yield Fact**
It's essential to remember that hand hygiene is the most critical component of infection control, and healthcare workers should wash their hands frequently, especially after interacting with patients or handling contaminated surfaces.

**Correct Answer: D.** Using a combination of hand hygiene, personal protective equipment, and environmental cleaning and disinfection, including quaternary ammonium compound (quat) or a hydrogen peroxide-based disinfectant, is the best way to control MRSA infection.