Lacunar infarcts may manifest all of the following except:
## Core Concept
Lacunar infarcts are a type of ischemic stroke caused by the occlusion of small penetrating arteries deep within the brain. They are typically associated with chronic conditions such as hypertension and diabetes mellitus. These infarcts are usually small (less than 2 cm in diameter) and often occur in the basal ganglia, thalamus, internal capsule, brainstem, and deep white matter.
## Why the Correct Answer is Right
Lacunar infarcts are characterized by their small size and specific locations within the brain. They result from the lipohyalinosis and fibrinoid necrosis of small penetrating arteries. The manifestations of lacunar infarcts can include pure motor hemiparesis, pure sensory stroke, sensorimotor stroke, ataxic hemiparesis, and dysarthria-clumsy hand syndrome. Cortical symptoms such as aphasia, agnosia, or visual field defects are typically not associated with lacunar infarcts because they involve deeper structures rather than the cerebral cortex.
## Why Each Wrong Option is Incorrect
- **Option A:** Pure motor hemiparesis is a classic presentation of lacunar infarcts, often due to lesions in the internal capsule or pons.
- **Option B:** Ataxic hemiparesis can also be a manifestation, usually resulting from lesions in the posterior limb of the internal capsule or the pons.
- **Option C:** Dysarthria-clumsy hand syndrome is another recognized syndrome associated with lacunar infarcts, typically due to lesions in the genu of the internal capsule or the pons.
- **Option D:**
## Clinical Pearl / High-Yield Fact
A key clinical pearl is that lacunar infarcts are often associated with small, deep infarctions and typically present with one of the five classic lacunar syndromes: pure motor hemiparesis, pure sensory stroke, sensorimotor stroke, ataxic hemiparesis, and dysarthria-clumsy hand syndrome. The absence of cortical symptoms like aphasia or agnosia can help differentiate lacunar infarcts from other types of strokes.
## Correct Answer: D.