## Core Concept
Infantile spasms, also known as West syndrome, are a type of seizure disorder that typically affects infants. Tuberous sclerosis complex (TSC) is a genetic disorder that can cause infantile spasms. The first-line treatment for infantile spasms associated with TSC involves specific antiepileptic medications.

## Why the Correct Answer is Right
The correct answer, **Vigabatrin**, is the drug of choice for treating infantile spasms associated with tuberous sclerosis complex. Vigabatrin works by inhibiting the action of GABA transaminase, an enzyme responsible for the breakdown of the neurotransmitter gamma-aminobutyric acid (GABA). By increasing GABA levels, vigabatrin helps reduce seizure activity. Studies have shown that vigabatrin is particularly effective in treating infantile spasms in patients with TSC, often leading to complete cessation of spasms.

## Why Each Wrong Option is Incorrect
- **Option A:** While adrenocorticotropic hormone (ACTH) is used to treat infantile spasms, it is not the first-line treatment for those specifically associated with tuberous sclerosis complex.
- **Option B:** Levetiracetam is another antiepileptic medication but is not considered the first-line treatment for infantile spasms in the context of TSC.
- **Option D:** Clobazam is a benzodiazepine used in the treatment of epilepsy but is not the drug of choice for infantile spasms associated with TSC.

## Clinical Pearl / High-Yield Fact
A key point to remember is that vigabatrin is specifically recommended as the first-line treatment for infantile spasms in patients with tuberous sclerosis complex, and its use is supported by strong clinical evidence. Monitoring for potential side effects, such as visual field defects, is crucial.

## Correct Answer Line
**Correct Answer: C. Vigabatrin**