**Core Concept**
In infants born to mothers with heart disease, the risk of developing congenital heart disease is significantly higher. This is due to the increased risk of congenital anomalies, particularly those affecting the heart and great vessels.

**Why the Correct Answer is Right**
The exact mechanism is not fully understood, but it is believed to be related to the increased risk of genetic mutations and altered maternal-fetal circulation during pregnancy. Infants born to mothers with heart disease are also at a higher risk of developing fetal distress, preterm labor, and low birth weight.

**Why Each Wrong Option is Incorrect**
* **Option A:** Fetal distress is indeed increased in infants of heart disease patients due to the altered maternal-fetal circulation and increased risk of preterm labor.
* **Option B:** Low birth weight is also a common complication in infants born to mothers with heart disease, likely due to the increased risk of preterm labor and fetal distress.
* **Option C:** Maternal-fetal hemorrhage is not directly related to the increased risk of congenital heart disease in infants.

**Clinical Pearl / High-Yield Fact**
Infants born to mothers with heart disease are at a higher risk of developing congenital heart disease, particularly those with structural anomalies. This highlights the importance of thorough prenatal evaluations and timely referrals to specialists in high-risk pregnancies.

**Correct Answer:** C. Maternal-fetal hemorrhage