Inclusion body conjunctivitis true in all except-
**Core Concept**
Inclusion body conjunctivitis is a highly contagious ocular infection caused by Chlamydia trachomatis, characterized by the presence of characteristic intracytoplasmic inclusions in conjunctival epithelial cells. It is often associated with a distinct clinical presentation and can be differentiated from other forms of conjunctivitis.
**Why the Correct Answer is Right**
The correct answer is related to the characteristics of inclusion body conjunctivitis. Chlamydia trachomatis, the causative agent, has a unique life cycle that involves both elementary and reticulate bodies. The reticulate body is responsible for replication within the host cell, whereas the elementary body is the infectious form that exits the host cell to infect other cells. Inclusion body conjunctivitis is typically caused by serovars D-K of Chlamydia trachomatis.
**Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because inclusion body conjunctivitis is indeed characterized by the presence of intracytoplasmic inclusions in conjunctival epithelial cells.
- **Option B:** This option is incorrect because inclusion body conjunctivitis is a highly contagious ocular infection caused by Chlamydia trachomatis, not by a viral agent.
- **Option C:** This option is incorrect because inclusion body conjunctivitis is typically caused by serovars D-K of Chlamydia trachomatis, not by serovars A-C.
**Clinical Pearl / High-Yield Fact**
Inclusion body conjunctivitis is often associated with a distinct clinical presentation, which includes a bilateral follicular conjunctivitis, mucopurulent discharge, and a characteristic "tarsal plate" appearance. This clinical presentation is often referred to as "trachoma" and is a major cause of blindness worldwide.
**Correct Answer:** D