Features of SLE include all of the following except –
**Core Concept**
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder characterized by a wide range of clinical manifestations, including skin, joint, renal, and hematological involvement. The disease is known for its ability to affect multiple organs and systems, making diagnosis and management challenging.
**Why the Correct Answer is Right**
Sterility is not a characteristic feature of SLE. In fact, many women with SLE are fertile and can conceive, although they may experience complications during pregnancy. This is in contrast to other autoimmune disorders, such as Antiphospholipid Syndrome (APS), which is associated with recurrent miscarriage and infertility. The incorrect association of sterility with SLE may be due to the presence of other autoimmune disorders that can cause infertility, such as APS.
**Why Each Wrong Option is Incorrect**
**Option A:** Recurrent abortion is a feature of SLE, particularly in the presence of Antiphospholipid Syndrome (APS). This condition is characterized by the presence of anti-phospholipid antibodies, which can cause recurrent miscarriage and fetal loss.
**Option C:** Coomb's positive hemolytic anemia is a feature of SLE, resulting from the production of autoantibodies against red blood cells. These autoantibodies can cause hemolysis and anemia, which is often seen in SLE patients.
**Option D:** Psychosis is a feature of SLE, particularly in the context of severe disease activity. SLE patients may experience a range of psychiatric symptoms, including depression, anxiety, and psychosis, which can be triggered by the disease itself or by the side effects of medications.
**Clinical Pearl / High-Yield Fact**
It is essential to distinguish between SLE and other autoimmune disorders that can cause recurrent miscarriage and infertility, such as APS. A thorough evaluation of the patient's medical history, laboratory results, and clinical findings is necessary to make an accurate diagnosis.
**Correct Answer:**
β Correct Answer: B. Sterility.