In which pattern does inheritance of Dupuytren’s contracture takes place?
Correct Answer: Autosomal dominant
Description: Dupuytren's contracture is a condition characterized by a flexion deformity of one or more fingers, nodular hyperophy and contracture of superficial palmar fascia (palmar aponeurosis). Dupuytren's contracture is inherited in an autosomal dominant pattern and is more common in males than females. The prevalence increases with age, but onset at early stage usually means aggressive disease. Ref: Maheshwari 3/e, Page 256-57; Apley's 8/e, Page 343-344.
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