In which of the following age group myelodysplastic syndromes (MDS) are most common?
Correct Answer: >50
Description: Idiopathic MDS is a disease of the elderly; the mean age of onset is 68 years. There is a slight male preponderance. MDS is rare in children, but monocytc leukemia can be seen. Therapy- related MDS is not age-related and may occur in as many as 15% of patients within a decade following intensive combined modality treatment for cancer. So the single best answer of choice is '>50'. Ref: Harrison's Principles of Internal Medicine, 16th Edition, Pages 624-25; R Alagappan Manual of Practical Medicine, 3rd Edition, Page 352-53.
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