In vitamin B12 deficiency, folate is trapped in the form of
Correct Answer: Methyl-THFA
Description: Methylation of homocysteine to methionine is the only way of regeneration of active THFA from methyl THFA. Methionine synthase reaction requires methyl cobalamin. So, deficiency of methyl-B12 leads to trapping of THFA in less utilised methyl-THFA - phenomenon known as folate trap.
Category:
Biochemistry
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