**Question:** In uveitis, site of keratic precipitate is:

A. Corneal endothelium
B. Anterior chamber angle
C. Corneal stroma
D. Posterior chamber

**Core Concept:**
The keratic precipitate (KP) is a white, flocculent, or granular deposit seen on the corneal endothelium in conditions affecting the anterior segment of the eye, particularly in uveitis.

**Why the Correct Answer is Right:**
In uveitis, the keratic precipitate is formed due to the deposition of immune complexes on the corneal endothelium. It is a diagnostic tool to indicate the presence of inflammation in the anterior chamber and to differentiate between anterior uveitis and posterior uveitis.

**Why Each Wrong Option is Incorrect:**
A. Corneal endothelium is the correct answer because it is where the keratic precipitate forms due to immune complex deposition during anterior uveitis.

B. Anterior chamber angle is incorrect because the KP is formed on the corneal endothelium, not within the angle where the iris and cornea meet.

C. Corneal stroma is incorrect as the keratic precipitate forms on the corneal endothelium, not within the corneal stroma.

D. Posterior chamber is incorrect because the KP is formed in the anterior segment of the eye, specifically on the corneal endothelium and not within the posterior chamber.

**Clinical Pearl:**
The presence and pattern of keratic precipitates can provide valuable information about the type and severity of uveitis and guide the physician to determine the appropriate treatment plan. For example, a linear pattern suggests anterior uveitis, while a circular pattern indicates posterior uveitis.

In summary, the correct answer is option A, as the keratic precipitate is formed on the corneal endothelium during anterior uveitis. The other options are incorrect due to their specific anatomical locations, which do not correspond to the formation of the keratic precipitate.