Pharmacology In the management of diabetes mellitus, lactic acidosis is commonly caused by which of the following: March 2005 A Tolbutamide B Glipizide C Pioglitazone D Metformin 💡 Explanation In the management of diabetes mellitus, lactic acidosis is commonly caused by which of the following: March 2005 ✓ Correct Answer: D. Metformin